Degradation of thymidine by Lactobacillus acidophilus.

نویسندگان

  • R V Sawula
  • S Zamenhof
  • P J Zamenhof
چکیده

Whole cells of Lactobacillus acidophilus are capable of degrading thymidine to thymine, suggesting the presence of thymidine phosphorylase (or thymidine hydrolase). This activity was also demonstrated in cell-free extracts.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Antiproliferative effects of homogenates derived from five strains of candidate probiotic bacteria.

Unheated and heat-treated homogenates were separately prepared from candidate probiotic bacteria, including Lactobacillus rhamnosus GG, Bifidobacterium lactis, Lactobacillus acidophilus, Lactobacillus delbrueckii subsp. bulgaricus, and Streptococcus thermophilus. We compared the phytohemagglutinin-induced proliferation of mononuclear cells in the presence of homogenates and in the presence of a...

متن کامل

Oxalate consumption by lactobacilli: evaluation of oxalyl-CoA decarboxylase and formyl-CoA transferase activity in Lactobacillus acidophilus.

AIMS This study was undertaken to evaluate the oxalate-degrading activity in several Lactobacillus species widely used in probiotic dairy and pharmaceutical preparations. Functional characterization of oxalyl-CoA decarboxylase and formyl-CoA transferase in Lactobacillus acidophilus was performed in order to assess the possible contribution of Lactobacillus in regulating the intestinal oxalate h...

متن کامل

Effects of Lactic Fermentation by Lactobacillus acidophilus and Lactobacillus plantarum on Antioxidant Characteristics and Lipase and Lipoxygenase Activities of Wheat Germs

Background and Objectives: Wheat germ is the most nutritious part of wheat grains, which has a short shelf-life due to its high lipid contents and presence of lipase and lipoxygenase enzymes. Thus, wheat germs are separated from the whole wheat grains during the flouring process, mostly used as animal foods. The objective of this study was to investigate effects of fermentation by Lactobacillus...

متن کامل

P-36: Evaluating The Effect of Lactobacillus Acidophilus and Bifidobacterium on Spermatogenesis Index of Testicular Tissue in Isoniazid-Induced Rats

Background: Isoniazid is an important drug in first line of treating the tuberculosis disease. This drug can lead to damages in different parts of the body such as liver and testis. Lactobacillus acidophilus and Bifidobacterium are the probiotics that have the important innate property that inhibit from passing of Isoniazid into the blood-testis-barrier. In point of spermatogenesis indexes whic...

متن کامل

The inhibitory effect of a Lactobacillus acidophilus derived biosurfactant on Serratia marcescens biofilm formation

Objective(s):Serratia marcescens is one of the nosocomial pathogen. The ability to form biofilm is an important feature in the pathogenesis of S. marcescens. The aim of this study was to determine the anti-adhesive properties of a biosurfactant isolated from Lactobacillus acidophilus ATCC 4356, on S. marcescens strains. Materials and Methods: Lactobacillus acidophilus ATCC 4356, was selected a...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Journal of bacteriology

دوره 117 3  شماره 

صفحات  -

تاریخ انتشار 1974